Volume: 1 Issue: 1
Year: 2025, Page: 8-14,
Received: July 11, 2024 Accepted: Nov. 20, 2024 Published: April 22, 2025
The current study investigation's objectives were to extract the plant Anthocephalus cadamba, screen it for phytochemicals, and assess the plant's in vitro antibacterial and antifungal properties. The present study includes the extraction with methanol and screening of various active chemical constituents of whole plant of Anthocephalus cadamba that exhibit antibacterial & antifungal activity. To estimate the levels of several phytochemicals, including phenolic, flavonoid, tannin, carbohydrate, steroid, glycoside, and mucilage content, the entire Anthocephalus cadamba plant was screened. In the current study, conventional protocols are used to test the antibacterial and antifungal activities of methanol extractions in vitro. The investigation was accomplished using agar well diffusion method. Outcomes of Phytochemical analysis of Anthocephalus cadamba revealed that the plant possesses strong antibacterial & antifungal activity potentials. The zone of inhibition for methanol extract against Staphylococcus aureus at 100μL was found to be 4.8 mm. The zone of inhibition for methanol extract at 100μL against Escherichia coli was found to be 3.0 mm and the zone of inhibition for standard drug ampicillin was found to be 6.2mm for Staphylococcus aureus & 8.4 mm for Escherichia coli correspondingly. Anthocephalus cadamba is used in Indian herbal medicine, and its antibacterial qualities may be due to the presence of bioactive chemicals in the plant. The evidence found from contemporary study deliver valuable data that will be supportive in identifying and to perform upcoming research in future
Keywords: Anthocephalus cadamba, Methanol, zone of inhibition, In vitro antibacterial activity
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